Hairy cell leukaemiaUploader: Dorr 5 years ago Subscribe 5
More than half of people respond partially to splenectomy. Not everyone needs treatment immediately. TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia. Most patients show an excellent longterm response to treatment with single-agent cladribine or pentostatin, with or without the addition of an anti-CD20 monoclonal antibody such as rituximab. A few studies have reported the beneficial effects of splenectomy. If your spleen is enlarged , it's likely you'll have a painful lump on the left side of your abdomen.